Chinese name: Ornidazole
English name: Ornidazole
CAS No.: 16773-42-5
Molecular formula: C7H10ClN3O3
Molecular weight: 219.63
EINECS No.: 240-826-0
Pharmacology of ornidazole
Ornidazole is the third generation nitroimidazole anti anaerobic drug widely used in clinic after metronidazole and tinidazole. Pharmacodynamics Ornidazole mainly interacts with cell components in the form of drug prototypes or active metabolites, leading to the death of pathogenic bacteria. Preliminary studies have shown that this drug is effective against Crohn's disease, but the comparative studies between this drug and other nitroimidazole drugs are limited. The mechanism of action is in vivo, and the drug is a cytotoxic drug prototype or active metabolite. The DNA that acts on the cells of anaerobes, amoebas, giardia and trichomonas can break their spiral structures or block their transcription and replication, leading to their death, so as to achieve the purpose of antibacterial and antigenic biology. Antibacterial spectrum anaerobic bacteria: Bacteroides fragilis, Bacteroides diricholi, Bacteroides ovalis, Bacteroides pleomorphis, Bacteroides vulgaris, Clostridium, Eubacterium, Digestive coccus and Streptococcus, Helicobacter pylori, Bacteroides melanogenes, Fusobacterium, CO2 Vibrio, and Bacteroides gingivalis. Parasites: trichomonas, giardia, amoeba.
This product is applicable to infections caused by sensitive microorganisms and anaerobes.
1. Genitourinary tract infection caused by trichomonas.
2. Intestinal and hepatic amoebiasis caused by amoeba protozoa (including amoebic dysentery and amoebic liver abscess).
4. Anaerobic infection: such as sepsis, meningitis, peritonitis, wound infection after surgery, postpartum sepsis, septic abortion, endometritis and other infections caused by sensitive bacteria.
5. Prevent anaerobic infection after various operations.